Istradefylline forty mg/day elevated peak concentrations and AUC of CYP3A4 substrates in scientific trials. This impact wasn't observed with istradefylline twenty mg/working day. Consider dose reduction of delicate CYP3A4 substrates.phenobarbital will minimize the extent or result of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism… Read More